Isaac Guerendo, 49ers

Latest update on Isaac Guerendo’s knee brings positive news for the 49ers ahead of the 2025 NFL season
The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, there’s still a long road ahead to determine if his recovery will be complete in time for the upcoming NFL season.
49ers RB Isaac Guerendo carted off with knee and ankle injuries
San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers' season finale versus the Arizona Cardinals. On San Francisco's opening series and on Guerendo's second carry,
MRI reveals 49ers RB Isaac Guerendo suffered MCL, ankle sprains
San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL injury.
49ers running back Isaac Guerendo carted off with leg injury
Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ season finale in Arizona against the Cardinals with a leg injury.
49ers’ Isaac Guerendo Suffers Injury in Season Finale vs. Cardinals
Unfortunately, San Francisco 49ers' running back Isaac Guerendo was carted off the field early in the first quarter.
49ers RB Isaac Guerendo shares positive injury update
San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the first offensive drive. He was
49ers' Isaac Guerendo: Has MCL, ankle sprains
Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, but he didn't damage the ACL in his left knee during Sunday's loss at Arizona, Matt Barrows of The Athletic reports.
49ers' Isaac Guerendo Says His 'ACL Is Good' After Being Carted Off with Injury
San Francisco 49ers running back Isaac Guerendo gave a positive update on his knee injury Monday, noting he did not tear his ACL as some had speculated:
Is Isaac Guerendo playing this week? Injury updates for 49ers RB
RB Isaac Guerendo was dealing with a hamstring injury. Here are the latest updates leading up to Week 17’s game vs. the Lions.
49ers running back Isaac Guerendo carted off with knee, ankle injuries
The 49ers have running backs Christian McCaffrey (knee), Elijah Mitchell (hamstring) and Jordan Mason (ankle) on injured reserve, which elevated Guerendo to the starting role Dec. 8. They have started five different running backs this season.
Standout 49ers rookie delivers positive update after scary Week 18 injury
The 49ers lost their standout rookie Isaac Guerendo in scary fashion. What update did the running back provide Monday?
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Should I Start Isaac Guerendo in Week 17? Fantasy Football Start 'Em, Sit 'Em Picks
Should I start or sit Isaac Guerendo for fantasy football in Week 17? Read our fantasy football start 'em, sit 'em picks and ...
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Kyle Shanahan Questions NFL Referees Decision Making As 49ers HC Announces Isaac Guerendo Injury Update
Even the officials are not being able to evade Kyle Shanahan's frustration this time. The post Kyle Shanahan Questions NFL ...
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49ers rookie may have avoided major injury in loss to Cardinals
San Francisco provided an initial injury update on RB Isaac Guerendo following the 49ers’ season finale vs. Arizona.
San Francisco 49ers
Rookie running back Isaac Guerendo was carted off the field early in the 49ers’ season finale in Arizona against the ...
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Isaac Guerendo A Healthy RB1 In Arizona
San Francisco 49ers rookie running back Isaac Guerendo (foot, hamstring) is off the injury report and ready to roll for a ...