Cells are thought to adopt mechanistically distinct migration modes depending on cell-type and environmental factors. These modes are assumed to be driven by mutually exclusive actin cytoskeletal ...

Cells can spontaneously change shape even without external signals, but the underlying mechanisms behind this form of ...

The architecture of the actin cortex determines the generation and transmission of stresses, during key events from cell division to migration. However, its impact on myosin-induced cell shape changes ...

Every time a white blood cell engulfs a bacterium, a neuron extends a projection to connect with a neighboring cell, or when a cancer cell forcefully squeezes through tissue to spread, the cell must ...

Chara corallina myosin XI (CcXI) drives the movement of actin filaments, which spontaneously form ring-like structures due to a slight curvature that leads to polar alignment. Living cells are highly ...

A microscopic image shows small red centers connected by networks of branched and straight filaments. The team mixed purified actin monomers with precise concentrations of two nucleation-promoting ...