Like many viruses, SARS-CoV-2 relies on lipid modifications carried by host enzymes to organize their membrane structure and coordinate the function of virulence proteins. Scientists at EPFL have ...
Catalytic acylation lies at the heart of modern organic synthesis, enabling the selective installation of acyl groups onto nucleophilic centres such as alcohols, amines and thiols. By employing a ...
S-acylation is the process of chemically linking a lipid to protein via a thioester bond. It is an important process of the cell that regulates the localization and function of numerous proteins. It ...
The ability to acylate amines enantioselectively by using a small-molecule catalyst instead of an enzyme just got a bit easier. A Rutgers University group has made this challenging task more ...
There are four types of coronaviruses (CoVs), of which include Alpha, Beta, Gamma, and Delta coronavirus. Among them, Beta CoVs are positive-stranded, enveloped ribonucleic acid (RNA) viruses that ...