A new study shows p62-mediated Mallory-Denk body formation is an adaptive, protective response to alcohol-induced liver ...

Alcohol and its metabolites disrupt the gut barrier, leading to increased levels of pathogen-associated molecular patterns (PAMPs). These PAMPs trigger the recruitment and activation of immune cells, ...

In response to alcohol, various cellular and molecular changes occur in the liver, contributing to hepatic steatosis, inflammation and fibrosis. Hepatocytes exhibit increased production of reactive ...

Drinking too much alcohol can increase inflammation and harm your body. Alcohol use disorder is a leading cause of death in the US and Europe. Heavy alcohol use may worsen inflammatory conditions like ...