A multinational collaboration co-led by the Garvan Institute of Medical Research has uncovered a potential explanation for why some cancer patients receiving a type of immunotherapy called checkpoint ...
B cell activation and antibody class switching requires coordinated metabolic rewiring, with essential roles for amino acid transport, cholesterol metabolism, and prenylation in driving proliferation ...
Gene-edited regulatory B cells could suppress overactive immune responses, potentially helping in the treatment of autoimmune ...
Objective B-cell activating factor (BAFF) is essential for B-cell survival and innate immune activation, and its ...
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