Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever cells ...
New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...
Living cells constantly exchange ions (i.e., charged particles) via the thin barrier that surrounds their interior, known as ...
While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...
Breast cancer stem cells (BCSCs), or “tumour-initiating cells”, comprise a subpopulation of cancer cells within the tumour that have extended longevity, are able to self-renew and produce progeny that ...
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...
Post-transplant complications reduce allograft and recipient survival. Current approaches for detecting allograft injury non-invasively are limited and do not differentiate between cellular mechanisms ...
As people age, their immune systems deteriorate. This makes them more susceptible to infections and can mean that vaccines are less effective. New research carried out by Dr. Loren Kell at NDORMS ...
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