RNA has emerged as one of the most promising molecules in modern medicine, enabling advances from mRNA vaccines and gene ...

Despite being made from a relatively simple set of building blocks, ribonucleic acid (RNA) has a broad array of complex responsibilities. From providing structure to carrying the instructions for ...

This diagram depicts the chemical structure of pyrimidine, a six-membered aromatic ring with two nitrogen atoms at positions 1 and 3 (highlighted in blue). The remaining positions are occupied by ...

About 95 % of human genes can produce different RNAs through a process called 'alternative splicing'. If you have ever read about cells, genes or DNA, you must have heard about RNA also. Chemically, ...

SANTA CRUZ, CA — Researchers at the University of California, Santa Cruz, have determined the three-dimensional structure of an RNA enzyme, or “ribozyme,” that carries out a fundamental reaction ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

A DNA-guided CRISPR platform could make RNA detection and control more stable, scalable, and precise, opening new routes for diagnostics, transcriptome engineering, and future therapeutic research.

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...