Plasmodium falciparum is responsible for the most virulent form of human malaria. This protozoan parasite spends part of its lifecycle inside the red blood cells (RBCs) of its host. The mature human ...

Calcium is essential for the correct functioning of the cell and requires regulation to avoid high concentrations causing cell death. Calcium ions are important for cell signaling as the binding of ...

Malaria vaccine shows over 50% efficacy in adults following controlled human malaria infection, supporting further trials in children.

Malaria continues to place a substantial burden on many emerging economies, contributing to significant loss of life, ...

KAE609 (cipargamin; formerly NITD609, Novartis Institute for Tropical Diseases) is a new synthetic antimalarial spiroindolone analogue with potent, dose-dependent antimalarial activity against asexual ...

A major tool against malaria in Africa has been the use of rapid diagnostic tests, which have been part of the 'test-treat-track' strategy in Ethiopia, the second most-populated country in Africa. But ...

Mali: A phase 2 randomized controlled trial published in The Lancet Infectious Diseases has revealed that a multistage malaria vaccine provided encouraging protection against controlled human malaria ...

Australian researchers have worked with global phamarceutical company MSD to co-develop a new antimalarial drug candidate ...

The evolutionary path of the deadliest human malaria parasite, Plasmodium falciparum, has been revealed for the first time. This parasite is a member of the Laverania parasite family that only infect ...

Malaria parasites survive tough times by not being too clingy. During Africa’s dry season, when mosquitoes are scarce, malaria parasites have a hard time spreading to new hosts. So the parasites hide ...