HER2 normally helps control the growth and repair of your cells, but too much of it can trigger HER2-positive cancer to develop. Generally, HER2-negative breast cancers tend to be less aggressive and ...

Human epidermal growth factor receptor 2 (HER2) proteins are found on the surface of breast cells and are involved in normal cell growth. Too much HER2 protein, however, can cause some types of breast ...

Enhertu showed better outcomes in HR-positive, HER2-negative breast cancer, while Trodelvy was more effective in HR-negative, HER2-null tumors when used first. Real-world data from over 4,000 patients ...

Breast cancer is a complex disease with many types. Understanding the specific type and classification of the breast cancer you have is crucial so that you can fully participate as an informed partner ...

In a 36-year-old woman with a resected 5-cm, node-negative, estrogen-receptor (ER)-negative, progesterone-receptor (PR)-positive, HER2-neu-negative breast cancer, is there a role for the addition of ...

Patients and Methods: Univariate and multivariate Cox proportional hazards regression models and Kaplan-Meier disease-free and overall survival estimate methods were used. Conclusion: HER-2/neu ...

The FDA expanded the approval of trastuzumab deruxtecan (T-DXd, Enhertu) to include treatment of unresectable/metastatic hormone receptor (HR)-positive, HER2-low ...