In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Here, Aaron Wenger, Principal Scientist – Bioinformatics at PacBio (CA, USA), explores how advances in accuracy, throughput and cost are making long-read sequencing more accessible at scale. Advances ...

DNA forms the informational basis of Terran life through its ability to store, transmit, and evolve genetic information. Two features let it do so: 1) rules of base pairing (i) size complementarity ...

Over the last 10 years, breakthroughs in understanding the genetic instructions passed from parent to offspring have put researchers closer than ever before to efficiently decoding DNA with 100% ...

Genome editing lets scientists rewrite DNA, the instruction manual inside every living cell, with a precision that was unthinkable a generation ago. Technologies such as CRISPR have made this almost ...

Twenty-five years ago today, on July 7, 2000, the world got its very first look at a human genome — the 3 billion letter code that controls how our bodies function. Posted online by a small team at ...

A new test provides a much more complete picture of DNA than current standard diagnostics and leads to a diagnosis more often ...

Researchers show long-read genome sequencing improves rare disease diagnosis and can replace multiple standard tests. By ...

Cancer genome studies have accelerated the discovery of novel diagnostic, prognostic and therapeutic biomarkers. Prospective sequencing of cancer biopsies is now routine in clinical oncology and ...