A newly identified molecule called OLE helped restore the brain’s immune cells to a more protective state in Alzheimer’s ...

Tiny immune cells called microglia protect the central nervous system (CNS) in a multitude of ways: They provide innate immunity, shape neurodevelopment, maintain homeostasis and modulate neurological ...

In the search for answers about Alzheimer’s disease, researchers are taking a close look at the immune system of the brain. A new study uncovers how a key immune cell, called a microglia, might be the ...

Microglia are specialized immune cells in the brain. While they normally protect our brains, they can also contribute to neurodegenerative diseases such as Alzheimer's. The exact mechanism behind this ...

Researchers identified OLE, a molecule derived from the PM20D1 gene, that reprograms microglia into a more protective state ...

Microglia appear activated in the vicinity of amyloid beta (Aβ) plaques, but whether microglia contribute to Aβ propagation into unaffected brain regions remains unknown. Using transplantation of wild ...

From anemia to leukemia, unhealthy cells can make for unhealthy people, but replacing these cells can help patients. What if the same were true for some of the world’s most devastating neurological ...

Researchers discovered that mutations linked to blood cancers may help trigger Alzheimer’s disease by creating overly ...

The role of microglia in spinal cord injury (SCI) remains ambiguous, partially due to the paucity of efficient methods to discriminate these resident microglia with blood-derived monocytes/macrophages ...

A researcher with the Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases at UT Health San Antonio has received a two-year, $402,500 grant award from the Cure Alzheimer's Fund to ...

Scientists reprogram brain immune cells to fight Alzheimer's: Study ...