A new study published in PLOS Genetics has identified an extreme mutational hotspot within the genome of Pseudomonas ...

A new technique, TF-High-Evolutionary (TF-HighEvo), allows large-scale assessment of de-novo mutations in multicellular organisms. Developed in collaboration with researchers from the European ...

Mutation dynamics in bacterial populations underpin the generation of genetic diversity that drives adaptation, speciation and the emergence of antimicrobial resistance. Spontaneous base substitutions ...

Community-based patient navigation and preventative care among women surviving breast cancer. Gentian violet compared with methylene blue for sentinel lymph node biopsy in breast cancer: A ...

A new study from deCODE genetics uses pedigrees and sequence data from 64,806 Icelanders to shed light on the rate and nature of mutations in mitochondrial DNA (mtDNA) and the peculiar dynamics of its ...

The William H. Foege Genome Sciences Building at the University of Washington School of Medicine in Seattle contains laboratories, sequencers, computational facilities, and other resources for ...

Using sequencing instruments from multiple vendors, scientists from the University of Utah Health, the University of Washington, PacBio, and elsewhere have developed what they claim is the most ...

Retrospective study of fluoropyrimidine chemotherapy dosing and toxicity in patients with screen-detected deleterious DPYD gene variants. Real-world treatment patterns, healthcare resource utilization ...

Mutation rate, as a biological process, denotes the frequency at which heritable changes in nucleotide sequence arise per genome, gene, or nucleotide per cell division or per unit time, driven by ...

Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive ...