Comparative genomic hybridization (CGH) provides a genome-wide scan that detects chromosomal regions which have copy number abnormalities (CNAs). For example, one can detect the loss of a region ...

The lack of molecular markers is a major factor contributing to the poor diagnosis and survival of women suffering from epithelial ovarian cancer. As reported in the January 30 Proceedings of the ...

Bicuspid aortic valve (BAV) is a common congenital heart defect where the aortic valve has two leaflets (cusps) instead of the usual three, resulting in abnormal blood flow and development of aortic ...

Microarrays have been a mainstay of the scientific research community for nearly a decade but given the more stringent demands for accuracy and reliability, have not been as closely embraced in the ...

Chief technology officer Don Montgomery explains that CombiMatrix's system synthesizes oligonucleotide probes directly on the chip through electrochemical methods. As a result, no mechanical parts are ...

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk—451 in all—through a whole-genome analysis that ranks as the largest ...