Ovarian cancer (OC) is the most deadly gynecological cancer and unlike most other neoplasms, survival rates for OC have not significantly improved in recent decades. We show that RAD6, an ...
Human DNA can be modified or damaged in a variety of ways that can alter its sequence and potentially change the information that it encodes, from UV radiation to chemicals in our own bodies. One way ...
The N-end rule and ubiquitin fusion degradation (UFD) pathways are ubiquitin-dependent proteolytic systems in Saccharomyces cerevisiae. Ubiquitylation of protein substrates in the N-end rule pathway ...