Chronic kidney disease (CKD) is a progressive condition marked by declining renal function, which predisposes patients to systemic metabolic imbalances. A prominent complication in CKD is vascular ...

In the hemodialysis population, cardiovascular calcifications result from excess phosphate and calcium, as well as reduced activity of inhibitors of calcification, such as matrix Gla protein. Vitamin ...

Renal transplantation does not stop or reverse coronary artery calcification (CAC), according to researchers. In a study that included 150 renal transplant recipients, CAC prevalence increased from 35 ...

Patients who form calcium kidney stones are more likely to have higher abdominal aortic calcification (AAC) and lower vertebral bone mineral density (BMD) scores than those who do not develop kidney ...

The arterial vasculature is the second most frequently calcified structure in the human body after the skeleton. Calcification of the aorta and aortic valves occurs in most individuals in westernized ...

Restoring ABCC6 function or enhancing its expression offers a new and compelling therapeutic strategy to prevent the progression of CKD towards end-stage renal disease in addition to reducing large ...

While diabetes and hypertension are well-known contributors to kidney disease, excess parathyroid hormone can silently elevate calcium levels, increasing the risk of recurrent kidney stones, kidney ...

Potent, selective ABCC6-targeting positive functional modulator (PFM) improved multiple markers of renal function in animal models of chronic kidney disease (CKD) PFM improved inorganic pyrophosphate ...

Experts warn that recurrent kidney stones and declining kidney function may signal a curable hormone disorder. TAMPA, ...