Ancient viral fossils buried in our DNA are offering fresh clues about how today’s respiratory pathogens infect and spread. By tracing the shared architecture between long-extinct retroviruses and ...

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have for the first time uncovered the detailed structure of the shell that surrounds the genetic material of ...

In the most comprehensive study of its kind, researchers report that most types of retroviruses have distinct, non-identical virus structures. In the most comprehensive study of its kind, researchers ...

In the most comprehensive study of its kind, researchers in the Institute for Molecular Virology and School of Dentistry at the University of Minnesota report that most types of retroviruses have ...

Researchers have solved the last unknown protein structure of HIV-1, the retrovirus that can cause AIDS. This will further explain how the virus infects human cells and how progeny viruses are ...

Figure 1: Nucleosome capture by the PFV intasome. Figure 2: Structure of the intasome–nucleosome complex. Using the nucleosomal structure as a landing platform may allow the viral machinery to sense ...

Integration of a cDNA copy of the viral RNA genome is essential to establish infection by retroviruses. This process (see, for example, ref. 10 for a review) is catalysed by the virus-encoded enzyme ...

The re-transcribed DNA is then integrated into the genome of the host cell (Figure 2). This process requires the absence of the nuclear membrane and thus is restricted to the M-phase of proliferating ...

LA JOLLA, CA—You are mostly but not entirely human. If we crunch the numbers, 8 percent of your genome actually comes from viruses that got stranded there. This viral detritus is a souvenir from our ...

You are mostly but not entirely human. If we crunch the numbers, 8 percent of your genome actually comes from viruses that got stranded there. This viral detritus is a souvenir from our evolutionary ...