The recent claim the long extinct dire wolf was resurrected made headlines around the world. But bioethicists and ecologists say there are ethical concerns.

For the first time in over 10,000 years, the howl of a dire wolf is echoing once more—this time, from within a secretive nature preserve in the United States. The predator, long thought extinct and famously mythologized in pop culture like Game of Thrones, is back, thanks to genetic engineering.