South San Francisco’s Carl Lutu #4 leads a moment of reflection after the Warriors lost to Colusa in the CIF NorCal 6-A high school football championship, Saturday, Dec. 2, 2023, in South San ...

The job cuts include technical and scientific roles and follow multiple rounds of layoffs over the past 18 months.

Genentech is planning a massive overhaul of its 207-acre South San Francisco campus that could cost between $3B and $5B by ...

Working on the steep slopes below San Bruno Mountain, workers apply paint to a 60-foot tall “S” letter, part of the “South San Francisco The Industrial City” sign, Tuesday, Sept. 19, 2023.

A word of warning if you're moving to South San Francisco: Normally, the welcome mat is out. It's been out since the late 1800s, when hard-working immigrants from Ireland, Portugal, Germany ...

Planned Parenthood closed 5 California clinics after Medicaid cuts, ending key services and impacting over 22,000 mostly Medi ...

SOUTH SAN FRANCISCO – A big mixed-use project in South San Francisco that will include a new Safeway store is pushing ahead with a real estate company’s purchase of a choice site for the development.

South San Francisco’s new skate park doesn’t look like much. There are no half pipes or handrails or complicated obstacles. It’s just a long stretch of flat ground with rectangular ledges ...

UPDATE: There is no merit to an “active shooter” at South San Francisco High School. Officers are now clearing the scene and the school has now lifted the lockdown. — SouthSanFranciscoPD ...

SOUTH SAN FRANCISCO – A 14-year-old from the South Bay has been detained in connection with a threat made against a school in South San Francisco, police said.