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In clinical practice, B6 toxicity is rarely about normal supplement doses - It’s almost always about poor clearance of this vitamin, not excess intake. After 30 years as a naturopath, what I see most often is impaired metabolism and excretion of this water soluble vitamin, driven by things like: • Liver congestion or reduced hepatic function • Kidney clearance issues (even mild or subclinical) • Magnesium deficiency (B6 is magnesium-dependent) • Zinc deficiency (required for B6 activation) • Vit
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